Menkman's work focuses on noise artifacts that result from accidents in both analogue and digital media (such as glitch and encoding and feedback artifacts). The resulting artifacts of these accidents can facilitate an important insight into the otherwise obscure alchemy of standardization via resolutions. The standardization of resolutions is a process that generally imposes efficiency, order and functionality on our technologies. It does not just involve the creation of protocols and solutions, but also entails the obfuscation of compromises and the black-boxing of alternative possibilities, which are as a result in danger of staying forever unseen or even forgotten Through her research, which is both practice based and theoretical, Menkman intends to uncover these anti-utopic, lost and unseen or simply "too good to be implemented" resolutions -- to find new ways to understand, use and perceive through and with our technologies.
In 2011 Menkman wrote the Glitch Moment/um, a little book on the exploitation and popularization of glitch artifacts (published by the Institute of Network Cultures), co-facilitated the GLI.TC/H festivals in both Chicago and Amsterdam and curated the Aesthetics symposium of Transmediale (2012). She have also been part of the curatorial team of Sonic Acts (2016-2017). Between 2012-2014, Menkman curated four exhibitions that illuminated the different ecologies in which glitch (art) developed. In 2015 she initiated the institutions for Resolution Disputes [i.R.D.], a solo show at Transfer Gallery New York. The i.R.D. are institutions dedicated to researching the interests of anti-utopic, lost and unseen or simply "too good to be implemented" resolutions. As an undertone, the show featured a showcase of the different complexities in compression (dots, lines, wavelets, blocks and vectors). In follow up exhibitions, Behind White Shadows (2017) and Shadow Knowledge (2020) and Im/Possible Images (2021) Menkman developed and highlighted the politics of resolution setting further, which resulted in a second book titled Beyond Resolution (i.R.D., 2020). In 2019 Menkman won the Collide, Arts at CERN Barcelona award, which came with a 3 month residency that inspired her recent research. From 2018 - 2020 she had a Vertretungs Professorship Neue Medien & Visuelle Kommunikation at the Kunsthochschule Kassel.